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Ming-Kuan Chyan Selected Research

Astatine-211

1/2021Evaluation of radioiodinated protein conjugates and their potential metabolites containing lysine-urea-glutamate (LuG), PEG and closo-decaborate(2-) as models for targeting astatine-211 to metastatic prostate cancer.
11/2019Investigation of a tellurium-packed column for isolation of astatine-211 from irradiated bismuth targets and demonstration of a semi-automated system.
6/2011Reagents for astatination of biomolecules. 5. Evaluation of hydrazone linkers in (211)At- and (125)I-labeled closo-decaborate(2-) conjugates of Fab' as a means of decreasing kidney retention.

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Ming-Kuan Chyan Research Topics

Disease

5Neoplasms (Cancer)
06/2011 - 05/2002
1Prostatic Neoplasms (Prostate Cancer)
01/2021
1Blood-Borne Infections
11/2019
1Infertility (Sterility)
01/2018
1Hematologic Neoplasms (Hematological Malignancy)
01/2018
1Lymphoma (Lymphomas)
07/2010

Drug/Important Bio-Agent (IBA)

4Radioisotopes (Radionuclides)IBA
01/2021 - 01/2008
3Astatine-211IBA
01/2021 - 06/2011
3Proteins (Proteins, Gene)FDA Link
01/2021 - 07/2010
3Indicators and Reagents (Reagents)IBA
06/2011 - 05/2004
3Biotin (Vitamin H)FDA Link
07/2010 - 05/2002
3StreptavidinIBA
07/2010 - 05/2002
1Lysine (L-Lysine)FDA Link
01/2021
1human FOLH1 proteinIBA
01/2021
1Glutamic Acid (Glutamate)FDA Link
01/2021
1Urea (Carbamide)FDA LinkGeneric
01/2021
1AntibodiesIBA
01/2018
1PyrogensIBA
01/2018
1Monoclonal AntibodiesIBA
06/2011
1GalactosamineIBA
07/2010
1DOTA-biotin (90Y-DOTA-biotin)IBA
07/2010
1Single-Chain AntibodiesIBA
07/2010

Therapy/Procedure

5Therapeutics
11/2019 - 05/2002
1Cell Transplantation
01/2018
1Radioimmunotherapy
05/2002